BDBM35589 pyrazolo pyrimidine, 21

SMILES CCNC(=O)Nc1ccc(cc1)-c1nc(N2CCOCC2)c2cnn(C3CCN(CC3)C(=O)OC)c2n1

InChI Key InChIKey=DCWBQVATVGTHLS-UHFFFAOYSA-N

Data  4 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 35589   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL

LigandBDBM35589(pyrazolo pyrimidine, 21)Copy SMILESCopy InChI

Affinity DataIC50:  490nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI